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Returning to the incretin effect, data has shown diminished insulin response to both incretins in patients with type 2 diabetes
Glucagon acts in the liver via cAMP (Halden et al., 2016)
These injections can either be administered by a medical professional or be self-administered and will start on a very low dosage, slowly increasing in amount each month before reaching the target dose to ensure no severe reaction to the medication occurs
Importantly, this transition does not necessitate any changes in formulation, stability or device function
The ideal candidate will also have a healthy endocrine system, not be pregnant or breastfeeding, and have no history of severe low blood sugar
