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Leptin, primarily released from fat tissue, signals the brain about the bodys energy reserves, while GLP-1, secreted by the intestinal tract in response to food intake, helps signal the brain when enough food has been consumed

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Some people may experience discomfort such as gas , bloating or stomach cramps when starting psyllium supplements, particularly if they begin with a high dose, [so] start with a lower dose and gradually increase it to minimize these effects, says Ingram

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