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Therefore, we need to understand the risks and benefits of these medications as well as understanding how to mitigate side effects

Weve also seen data that semaglutide has been shown to have anti-inflammatory and cardiovascular benefits, which can further protect the kidneys from damage. If the heart pumps better, Whyte added, the kidney is going to function better. The role of GLP-1 medications for treating obesity is just one of several surprising findings uncovered since their introduction to the market

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The finding that semaglutide, while leading to a quantitatively large improvement in HF-related symptoms and physical limitations in patients with NYHA functional class II, appears to have an even greater benefit in terms of improvement in KCCQ-CSS among those with more severe functional limitations (NYHA functional classes III/IV) is especially noteworthy.

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