metformin with glp 1 Similar cellular effects of metformin, GLP1-RA, DPP4i, and SGLT2i Frontiers | Advances in the
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10.1016/j.molcel.2020.09.020

Optimise nutritional intake by ensuring adequate protein (approximately 0.75g per kilogram body weight daily), iron-rich foods, and varied nutrient-dense meals despite reduced appetite

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The Icelandic Medicines Agencys alert regarding reports of suicidal thoughts and self-injury in individuals using liraglutide and semaglutide has raised concerns about the potential suicidal and/or self-injurious risk associated with GLP-1RA [8]

However, these studies have inherent limitations, primarily stemming from their controlled duration and predefined patient criteria [Reference Blackman, Foster, Zammit, Rosenberg, Aronne and Wadden22Reference Wadden, Hollander, Klein, Niswender, Woo and Hale26]
But when you eat significantly less food, you also take in fewer nutrients including protein
