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Understanding the medication's actual side effect profile helps patients and clinicians distinguish between established risks and coincidental symptoms

Indeed, obesity-driven defects in CD8+ TIL activation curtail the requirement for T cell extrinsic immune evasion to the point where tumors transplanted from obese mice into immunocompromised mice grow more slowly than those transplanted from never-obese control mice 8

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Fatigue is another commonly reported experience, particularly during the first weeks of treatment or after dose increases