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Most patients start at 2.5 mg once weekly for four weeks and then move to 5 mg once weekly

Values of T were also relatively consistent, ranging from 124 to 145 h (approximately 56 days), regardless of whether they were calculated over a period of less than or greater than the resultant T

In the SURMOUNT-1 trial, adults with obesity or overweight without diabetes experienced substantial average weight loss over 72 weeks with 5 mg, 10 mg, and 15 mg doses

This affects concentration but not total medication amount

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