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In the largest comparative effectiveness study of tirzepatide (Mounjaro) and semaglutide (Ozempic) for weight loss using real-world data now published in JAMA Internal Medicine Truveta Research found that patients with overweight or obesity taking tirzepatide were three times more likely to achieve 15% weight loss than those taking semaglutide

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Conclusion In this data sampling of German inpatients, more than one-third of ASCVD patients may qualify for GLP-1 RA therapy due to concomitant diabetes mellitus or obesity