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"Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity." New England Journal of Medicine

Based on Phase 3 trial data, Retatrutide appears to produce greater average weight loss than semaglutide (the active ingredient in Wegovy and Ozempic)

Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are approved for the treatment of type 2 diabetes and obesity

doi:10.1172/JCI105685 183

Deconstruction of a neural circuit for hunger

Forest plot of GLP-1 receptor agonists versus comparators on the risk of Pulmonary embolism
