is retatrutide a glp-1 Retatrutide for Weight Loss: TRIUMPH-1

Atkin Clinical Endocrinology.2014

Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus

In recent years, there has been an expansion of the armamentarium for T2DM treatment with drugs that are not limited exclusively to glycemic control but also have positive effects on reducing CV risk

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Other, smaller trials in patients who already have Alzheimers point both ways, with Edison et al reporting better executive scores and less temporal and whole-brain atrophy on liraglutide, while Gejl (n=38, 6 mo follow-up) and Mullins (n=21, 1.5 yrs follow-up) were neutral to negative, which is exactly what you expect from studies that are short, and not powered to read a slow, insidious disease

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