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Two people taking the same dose may experience vastly different outcomes based on these genetic differences

Therefore, the activation of the IGF-2/IGF-1R axis may contribute to -cell survival in response to GLP-1, and importantly, the increased IGF-2 secretion may be essential for triggering this response, as also observed in embryonic development (41)

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Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and dual GIP/GLP-1 receptor agonists like tirzepatide (Mounjaro, Zepbound) are injectable medications used for type 2 diabetes management and weight loss