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Tirzepatide has a dual-action mechanism that enhances insulin release but also plays a role in how your body stores fat

Nausea is the most frequently reported complaint, occurring in 28% of participants on the 12mg dose

These drugs were originally developed to treat diabetes but turned out to have this satiety effect and helped people lose weight because they just dont eat as much, Koren said

Finally, beyond their role in controlling metabolic processes, GLP-1 receptor agonists also show promising potential benefits in treating cardiovascular and neurodegenerative diseases

Mounjaro vs Wegovy: what the clinical trials actually show Mounjaro vs Wegovy: what the clinical trials actually show STEP and SURMOUNT: the individual trial results The STEP trials for semaglutide 2.4mg reported mean body weight loss of 14.9 to 17.4% at 68 weeks

Many patients begin to notice reduced hunger and fewer cravings within the first 13 weeks, which can make it easier to stick to a calorie deficit without feeling deprived