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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Aronne L.J., Halseth A.E., Burns C.M., Miller S., Shen L.Z
Dig Dis Sci (1993) 38:66573.10.1007/BF01316798 6 GutzwillerJPGokeBDreweJHildebrandPKettererSHandschinDet alGlucagon-like peptide-1: a potent regulator of food intake in humans
Because retatrutide acts on three receptors, some researchers call it a triple agonist. This design may explain why trial results gained so much attention
However, recent studies have shown their potential in weight management, leading to the development of medications specifically aimed at weight loss, such as Wegovy
Soluble fiber (found in oats, bananas, and apples) can paradoxically help some patients by forming a gel that slows intestinal transit, though insoluble fiber (wheat bran, raw vegetables) may worsen symptoms initially and should be introduced slowly
Weight Loss Reduces Knee-Joint Loads in Overweight and Obese Older Adults With Knee Osteoarthritis. Arthritis & Rheumatism
