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Heres what to consider: Gradual transition : If discontinuing GLP-1 receptor agonists, do so under medical supervision to prevent rapid weight regain

[DOI] [PubMed] [Google Scholar] 49.Davies M.J., Bergenstal R., Bode B., Kushner R.F., Lewin A., Skjth T.V., Andreasen A.H., Jensen C.B., DeFronzo R.A., NN8022-1922 Study Group Efficacy of Liraglutide for Weight Loss among Patients with Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial

Drawing 10 units versus 12 units is a 20% dose difference, which is significant when you are trying to maintain a precise starting dose

Further details regarding the characteristics of the included studies can be found in Tables 12

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However, a recent large meta-analysis showed no association between these three variants and low bone mineral density or fracture prevalence (102)