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This has led to widespread off-label use of diabetes GLP-1 doses

B., Sluiter, W

These can include: Nausea Diarrhea Vomiting Abdominal pain Constipation These digestive problems may become exacerbated in the absence of a gallbladder

Ozempic contains semaglutide GLP-1, a GLP-1 receptor agonist that works by increasing feelings of fullness, reducing appetite, and slowing stomach emptying

However, the clinical data suggests that the combined effect of all three receptor targets results in improved overall glycaemic control, with the GLP-1 and GIP effects appearing to counterbalance any blood sugar raising tendency from the glucagon component

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