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Growth hormone (GH) is an essential regulator of growth, body composition and fuel metabolism and, consequently, GH secretion is under the feedback control of numerous nutritional and endocrine mediators

However, it also turns out that interaction of GLP-1 agonists with receptors found on brain cells leads to feelings of satiety and reduced hunger

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Aims/hypothesis Insulitis, a hallmark of inflammation preceding autoimmune type 1 diabetes, leads to the eventual loss of functional beta cells

Secondary outcomes included the incidence of aborted EGDs due to GRC, the effect of concurrent CLN on GRC, and a comparison of GRC risk among different GLP-1 RA agents