glp-1 drugs cancer May Protect Against Cancer— Here's What That Means For Public Health Health Rounds: GLP-1 drugs linked
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We included 26 records regarding the safety of GLP-1 agonists during pregnancy and/or lactation ( Supplement 2 , 3 ), and 16 records regarding the safety of SGLT2 inhibitors during pregnancy and/or lactation ( Supplement 2 , 3 )
The Fast Facts The approval of Oral Wegovy and Rybelsus signals a significant advancement in GLP-1 medication
Clinical and meta-analytic data indicate that, although FBM reduction predominates, modest decreases in LBM can occur, particularly during substantial weight loss [17, 18]
Danuglipron, Pfizer's oral GLP-1 agonist, has had a more challenging development path, with an initial twice-daily formulation producing significant nausea rates that led to reformulation as a once-weekly oral tablet
These results suggest that the uptake of GLP-1RAs into the brain via tanycytes is important for their anti-obesity effects
N Engl J Med 2012;367:2204-13.ArticlePubMed 14
