best glp 1 program GLP-1 Support Supplement dose GLP The GLP-1 Solution: 175+ Strategies,

14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below

10.1038/s41398-020-00923-1 72 VallofD.MaccioniP.ColomboG.MandrapaM.JornulfJ

82073429, 82273510, 82430101), Innovation Program of Shanghai Municipal Education Commission (No.2019-01-07-00-07-E00046), Clinical Research Plan of SHDC (No.2020CR1014B, 22022302, 2020CR6022), Shanghai Science and Technology Development Funds (24YF2738100)

Authors relationships and activities TDM receives funding from Novo Nordisk and has received speaking fees from Novo Nordisk, Eli Lilly, Boehringer Ingelheim, Merck, AstraZeneca, Mercodia and Berlin Chemie AG

Median HbA1c decreased by 8.7 mmol/mol with metformin and 14.2 mmol/mol with GLP-1RA therapy

Talley, Email: [email protected]