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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), such as semaglutide (marketed as Ozempic and Wegovy), have gained widespread attention for their effectiveness in treating type 2 diabetes and aiding in weight loss
Tanday et al., (2022) have since described a role for Y1-R agonism in inducing periods of -cell rest that, when combined with GLP-1R agonism, proved beneficial in obesity-driven models of diabetes
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Additionally, females experienced greater pain relief than males, suggesting a potential gender-specific response to the treatment [62]
