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Safety concerns come with this wider use
2023 January;22(1):20-27 | doi: 10.12788/cp.0318 Evidence suggests substantial beneficial effects on weight and glycemic dysregulation

Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines

[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, Fainsinger RL, Jatoi A, Loprinzi C, MacDonald N, Mantovani G, Davis M, Muscaritoli M, Ottery F, Radbruch L, Ravasco P, Walsh D, Wilcock A, Kaasa S, Baracos VE

Orlistat (Xenical, Alli): A fat absorption inhibitor still in use but less favored

It helps in the following ways
