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Glucose homeostasis and insulin secretion models: Evaluation of glucose-dependent insulin secretion , glucagon modulation , and glucose tolerance in pancreatic islet systems and intact animal models

Singly housed male C57BL/6JRj mice were fed a 60 kcal% fat diet (Research Diets, D12492) for 16 weeks

The result is shown in Figure 2

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That distinction is explained in detail below, and it is the most important thing to understand before evaluating this program