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Important reminder for all in pharma especially in metabolic therapies to double-check marketing strategies against these guidelines

Evaluate caffeine intake and consider reducing it by 25-50% to account for body composition changes

Annett, V

2021;33:e12953

Alcohol can cause unpredictable changes in blood glucose, leading to both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar)

Cardiovascular Safety Studies With DPP-4 Inhibitors The Clinical Guidance for Pharmaceutical IndustryDiabetes MellitusEvaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes established by the FDA in 2008 as a consequence of adverse safety signals of rosiglitazone has set up the requirement for novel diabetes medications to prove cardiovascular safety of these substances in comparison to standard therapy under glycaemic equipoise