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Patients with higher baseline BMI (body mass index) or greater initial adiposity often achieve larger absolute weight losses, sometimes exceeding 30-40 pounds within the first year

Additionally, using semaglutide has been shown to significantly improve insulin sensitivity and the ability of pancreatic beta-cells to produce and secrete insulin

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Notably, the deals struck include an expansion of coverage of GLP-1s to include some Medicare patients who previously had no access to GLP-1s for obesity alone