glp 1 cons GLP-1 Agonists: Using Semaglutide, Tirzepatide, and Orforglipron for Weight Loss and Obesity GI Adverse Effects of Glucagon-Like
Description
These findings highlight significant variability in diabetes risk among young adults with prediabetes as well as the inadequacy of treating all patients with prediabetes in the same manner

Comorbidities such as cardiovascular disease, sleep apnea, or uncontrolled diabetes change priorities: reduce hypoglycemia risk, avoid volume depletion, and maintain glycemic targets that fit the procedures risk profile
GLP-1 Weight Loss & Plastic Surgery: The Restore SD Advantage Meaningful weight loss (even 20 to 40 pounds) can leave patients with loose skin on the abdomen, arms, and thighs, and changes in breast volume and shape

Nwako JG, McCauley HA

[DOI] [PubMed] [Google Scholar] 86.Witteles RM, Keu KV, Quon A, Tavana H, Fowler MB

There seems to be a size limitation at least for cytokines, where DPP4 is more prone to cleave substrates of around 24 amino acids (aa) length