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Circulation 139:e840e878 Ndumele CE, Rangaswami J, Chow SL, on behalf of the American Heart Association et al (2023) Cardiovascular-kidney-metabolic health: a Presidential Advisory from the American Heart Association

How to Know if Your Hunger Levels Are Acceptable A big question many people have is how much hunger is appropriate
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It's worth noting that these side effects can sometimes be linked to changes in blood sugar levels, particularly in individuals who are also managing diabetes
Consequently, on top of the beneficial effect of weight loss caused by GLP-1 analogues these drugs also cause a substantial reduction of the glycemic load (GL = carbohydrate intake X Glycemic index), which per se reduces hyperinsulinemia and causes weight loss [22], reduce diabetes risk [23], inflammation [24], and cardiovascular risk [25]
