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The SURMOUNT-1 study was a placebo-controlled 72-week trial in obese subjects that randomized 2,539 participants without diabetes into four equally large study arms with placebo or one of the three tirzepatide doses (5, 10, or 15 mg once weekly)

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While the patenting behavior around tirzepatide is still early in its life cycle as compared to semaglutide, it already demonstrates how Eli Lilly has built a thicket of patents that extends its patent protection

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Acute kidney injury has been reported, typically in the context of severe gastrointestinal adverse reactions leading to volume depletion