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Other medications that affect gastric motility (opioids, anticholinergics, prokinetics) should also be held per protocol

To date, we have learned that tirzepatide mainly stimulates insulin secretion through GIP receptor in human islets [149]

[4] The theoretical benefits of combining allulose with GLP-1 therapy centre on enhanced glycaemic control and weight management

GLP-1 exerts its anorectic effect in part by acting on the hunger-satiety centre located in the arcuate nucleus of the hypothalamus, and in part by delaying gastric emptying

Some studies have suggested that the proliferation and apoptosis of granulosa cells (GCs) are the root causes of follicular development and atresia, with forkhead box protein O1 (FoxO1) playing an important role in promoting PCOS follicular atresia and GCs apoptosis (162, 163)