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Body Composition Individuals with higher body fat percentages may experience a slower onset of effects compared to those with lower body fat, as the medication interacts with body systems differently

In obese and metabolic-risk populations, higher doses have produced weight loss of up to 15% of baseline body weight

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References Moiz A, Filion KB, Tsoukas MA, Yu OH, Peters TM, Eisenberg MJ

37 Neutrophils cause a highly viscous state in the airways and destroy the lung parenchyma by releasing various bioactive substances such as neutrophil elastase (NE), histone G and oxidative substances