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Tirzepatide as a novel effective and safe strategy for treating obesity: a systematic review and meta-analysis of randomized controlled trials

In 2023, Humphrey and Lawrence emphasized the importance for plastic surgeons to recognize these potential effects, counsel patients before initiating therapy, and consider both surgical and non-surgical interventions to mitigate facial volume loss, sagging, and premature aging [86]

The enzyme dipeptidyl peptidase-4 (DPP-4) chews through GLP-1 so quickly that its effects are fleeting

Postprandial lipemia associates with liver fat content

Emerging Safety Concerns Recent research has identified new safety considerations beyond traditional gastrointestinal effects

This finding underscores the importance of clinical physicians being aware of and conducting comprehensive patient history assessments before prescribing these medications