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GLP-1 receptor agonists are FDA-approved for weight management in adults with BMI 30 kg/m (obesity) or BMI 27 kg/m with at least one weight-related comor...

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This review examines the biological mechanisms underlying GLP-1 RA therapy in MASLD/MASH, analyzes the mechanistic distinctions between mono-, dual-, and triple agonists, and synthesizes current clinical evidence supporting their utilization in individuals with this condition.