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GLP-1 therapy may help by reducing the biological drive to overeat

The activation of cAMP-PKA signaling in gut IELs can inhibit the phosphorylation of Zeta-chain-associated protein kinase-70 (ZAP-70), stopping the signal from TCR, resulting in the inhibition of the immunological response of T cells (Wong et al., 2022

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Smriti Choudhary, M.D ., and Dr

However, along with their widespread prescription, there have been more and more reports regarding irreversible end-organ damage [2]

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