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This comprehensive approach can support conversations about whether Ozempic, compounded semaglutide alternatives, or other GLP-1 agents best match your genetic and metabolic profile, potentially improving tolerability and outcomes

The best choice depends on current weight and BMI, weight-related medical conditions, blood sugar status, cardiovascular risk, liver health, kidney function, medication history, side-effect risk, muscle mass and nutrition status, cost and access, patient preference, and long-term maintenance planning

, Douros, J

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Hormone replacement therapy combined with GLP-1 medications can be synergistic, particularly for perimenopausal and menopausal women or for men with low testosterone