semaglutide nature medicine Proteomic changes upon treatment with in individuals with obesity Semaglutide versus placebo in individuals

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Hartmann P, American Journal of Physiology Gastrointestinal and Liver Physiology (Vol 329, Issue 6, Dec 1, 2025, pp G680G695)

This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide).