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Within the gastrointestinal (GI) tract, GLP-1R localizes to vagal afferent fibers, enteric neurons, and Brunner glands [1820], and to gastric mucosa and smooth muscle cells that regulate gastric emptying [2123]
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These findings expand upon the growing body of literature raising concerns regarding the potential ocular safety of systemic GLP-1 RA use in patients with diabetes, investigators concluded
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