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Other types of mutations included indels in MITF and KTN1 genes (transcription factor and transmembrane kinesin receptor, respectively) and loss of heterozygosity (LOH) in the IDH1 gene that belongs to the dehydrogenase family

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(2) Treatment adherence was inferred from the proportion of days covered (days in which an individual had access to the medication during the prescription period during follow-up), and a level of adherence 80.0% was considered to constitute adherence to treatment

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Therefore, the R-isomer of ALA is believed to be the form that exerts most of the biologic effects of ALA

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Snchez-Garrido, M.A., Serrano-Lpez, V., Ruiz-Pino, F

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