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But Mehmet Oz, his nominee to run the Centers for Medicare and Medicaid Services, is a physician and television personality who has endorsed GLP-1 drugs in a sponsored segment on his show and still promotes the drugs on his website, the Washington Post reported

Hursting: Theres a constellation of metabolic changes that occur with obesity

Other GLP-1ssuch as Ozempic and Wegovy are approved for weight loss and diabetes management, which can still improve sleep apnea indirectly

If your BMI is 40+ and you need substantial weight reduction for health reasons, the 20-25% body weight loss achievable with tirzepatide vastly exceeds the 10% typical of Qsymia

has received consulting fees from Amgen, Eli Lilly and Esperion and speaker honoraria from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Merck Schering-Plough, Novartis, Novo Nordisk, Pfizer and Sanofi

A randomized trial with adolescents aged 1218 years with severe obesity evaluated the efficacy of topiramate in maintaining weight loss following a 4-week meal-replacement therapy [91].There was no statistically significant difference in percent BMI change between the topiramate and placebo groups after 28 weeks