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317 , E1081E1093 (2019)

Patients were randomized to TRESIBA injected once-daily at the same time each day (with the main evening meal), to TRESIBA injected once daily at any time each day or to insulin glargine U-100 injected once-daily according to the approved labeling

Its gradual onset, minimal peak, and long duration help stabilize fasting and overnight glucose when paired with consistent timing and careful titration

I view this volatility as due almost solely to the momentum factor unwind and having very little to do with the fundamental thesis

Store at room temperature (68F 77F / 20C 25C)