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While head-to-head comparison data are preferable where available, NMA is a robust statistical approach that facilitates indirect comparison of multiple treatment options when direct comparative data are not available

doi: 10.1126/sciadv.ado1820

Those closer to a healthy weight, or those without significant metabolic dysfunction, may see smaller percentage reductions: the drug is removing less to start with

[DOI] [PubMed] [Google Scholar] 656.Liu L, Simon B, Shi J, Mallhi AK, Eisen HJ

The CDC says that a BMI of 30 or higher puts you at risk for obesity-related health problems, including heart disease, diabetes, and some cancers

doi:10.1016/S0140-6736(17)31281-3