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Sardu C, Marfella LV, Fumagalli C, et al

What specifically do these medications do

An alternative emphasis on spatial localization of GcgR signaling for the mediation of downstream outcomes is the reliance of maximal hepatic transcriptional upregulation of genes such phosphoenolpyruvate carboxykinase 1 (PCK1), the rate-limiting enzyme in gluconeogenesis, on the full internalization of the ligand-bound glucagon receptor [21]

Frontiers in Pharmacology 2022;13:114

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Cefalu WT, Kaul S, Gerstein HC, Holman RR, Zinman B, Skyler JS, et al
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