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According to its authors, their study challenges the key role of carbohydrates in athletic performance and the belief that muscle glycogen (or an adequate supply of exogenous carbohydrates) is key and/or indispensable in maintaining long-term exercise performance

For a lifter, the proposed benefit is keeping that insulin-sensitive state intact deeper into a surplus, so the partitioning ratio stays friendlier for longer
J., Parving H.-H

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No method guarantees zero regain, but gradual tapering of medication combined with continued lifestyle changes offers the best chance for sustained weight management

As a result, researchers have begun exploring whether these pathways may also be relevant to conditions beyond diabetes and obesity
