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Furthermore, the risk of developing these inner ear disorders was observed in those with longer durations of GLP-1 RA exposure

As more patients and healthcare providers seek effective diabetes management solutions with minimal side effects, demand for GLP-1 receptor agonists is set to surge

The Intestinal Microenvironment and Functional Gastrointestinal Disorders
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Metformin and other drugs used for T2DM, like the SGLT2 inhibitors, may also reduce hyperglycemia-induced elevated endothelial ROS, independent of negative effects on complex 1, such as via inhibition of NADPH oxidase or blocking the entry of glucose into the endothelium (107109, 187, 188) ( Table 2 )

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