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In 2025, the drugs generated combined sales of $36.5 billion, comprising around 56% of the companys total revenues

FDA-approved GLP-1 medications have been shown in clinical studies to support weight management and metabolic health, but they often come with higher out-of-pocket costs, and insurance coverage varies widely

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10.1126/science.1072994 Science 25 HlscherC

The mRNA data presented here are consistent with previous reports on islets, lung, and stomach as being highly enriched for GLP-1R, and our results are further substantiated by western analyses showing strong GLP-1R protein signal in islets, lung, and stomach

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