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Your body adapts to the predictable presence of the medication, allowing your appetite-control centers to work optimally

Metformin, the cornerstone of T2DM therapy, activates AMP-activated protein kinase (AMPK), which has been shown to normalize SR/ER-mitochondria interactions ( 2+ overload (Wu et al., 2019)

The UK Chief Medical Officers' Physical Activity Guidelines emphasise the importance of strength training, and NICE guidance on weight management highlights physical activity

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Falling estrogen levels mean we lose muscle faster, store more fat around our middles, and become more insulin-resistant