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During the median follow-up of 15.9 months, 137 major adverse cardiovascular events (MACEs) (61/1591 patients (3.8%) in the oral semaglutide group and 76/1592 patients (4.8%) in the placebo group) were documented [52]

Diabetes (db/db) mutation-induced endometrial epithelial lipoapoptosis: ultrastructural and cytochemical analysis of reproductive tract atrophy

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Due to the high expression profile of GLP-1R in pancreatic -cells, GLP-1 analogs (such as exendin-4) have been modified by different methods (to prolong half-life, maintain receptor binding affinity and reduce renal drug accumulation) for theranostic purposes and serve as excellent templates for future cardiovascular drug development[178-184]

Specifically, triiodothyronine (T3) stimulates -cell proliferation from birth through the first week of life