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These additional activity pathways may explain why early studies suggest greater average weight loss with retatrutide

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Such ratio significantly increased from baseline after 26 weeks of treatment with liraglutide 1.8 mg/day, indicating a reduction in liver steatosis, whereas it was unchanged in patients treated with lower doses of liraglutide, glimepiride or placebo

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One of the biggest factors is insulin resistance, a key symptom of PCOS