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Skibickas lab has found that women, on average, lose more weight than men on equivalent doses, possibly due to interactions between GLP-1 signaling and estrogen

Deckelbaum, R

This allows semaglutide therapy to remain aligned with evolving metabolic indicators

Diabetes Obes Metab (2020) 23(4):10526

Glucagon-like peptide-1 (GLP-1)-based antidiabetic drugs have drawn particular attention as an effectual new strategy to not only regulate blood glucose but also decrease body weight by reducing appetite, which implies that GLP-1 could affect the gutbrain axis in normal and pathological conditions

Now, when were seeing GLP-1s, it is really important to say, Can this actually make a difference? If I were to objectively utilize this and am able to say, I have someone who has sleep apnea, I have someone who has insomnia, I have someone who has another sleep disorder, do we see any meaningful change