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Despite these high prescription numbers, the actual number of users may be even greater, as some obtain the medication without adequate medical supervision, often due to insurance limitations

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Methods Leveraging the target trial emulation framework, we conducted a retrospective study using observational data to emulate a new user, active comparator trial examining the effects of initiating GLP-1RA (exposure group) versus SGLT2 inhibitors (control group), with random treatment assignment emulated by propensity score matching with 1:1 ratio

doi: 10.1097/JOM.0000000000000099