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Through stimulation of pro-opiomelanocortin (POMC) neurons while simultaneously inhibiting neuropeptide Y/agouti-related peptide neurons in the arcuate nucleus, GLP-1 receptor agonism promotes satiety, reduces meal size, and decreases overall caloric intake [35]

Tirzepatide came in at 1.73 (95% CI: 1.42-2.09)

For protocols requiring 250 mcg or less, 3 mL works well since it keeps doses in the 5-10 unit range where accuracy is high

Participants in the metformin with CPA/EE group had a greater decrease in hyperandrogenemia than those in the metformin with the GLP-1 receptor agonist group [6]

Regular follow-ups allow your doctor to adjust your treatment plan based on how your body responds
