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About one in eight adults in the United States has used a GLP-1 drug at some point, with approximately six percent of adults more than 15 million people currently using a prescription
therefore, it is recommended to avoid GLP-1R agonists in patients with a past history or family history of medullary thyroid cancer or multiple endocrine neoplasia 2 [88,89,90]
doi: 10.1016/j.copbio.2020.08.009
Diabetic retinopathy Rapid improvements in glucose control have been associated with a temporary worsening of diabetic retinopathy
Thiazide diuretics increase the excretion of sodium, chloride, and water by inhibiting sodium ion transport across the renal tubular epithelium
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