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41 Overall, oral semaglutide, the single oral GLP1-RA agent, seems to be an effective and safe hypoglycemic agent in T2DM and might be considered as a promising future alternative option and an add-on therapy to further improve Hb1Ac and reduce weight, while securing a low risk of hypoglycaemic episodes

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Missing doses or inconsistent administration can reduce the medication's effectiveness and may increase the likelihood of side effects when you resume treatment

If you have an HSA or FSA, check whether those funds can be applied toward semaglutide costs

On one hand, the lack of approval means no established treatment protocols exist, insurance will not cover costs, and medical supervision may be limited