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(Gastric bypasses and sleeves are surgical methods that essentially reduce the size of the stomach.) Gastric sleeve recipient Courtney Paige says that, in hindsight, neither surgery nor GLP-1s are worth it

Diabetologia 1990;33:675680

Being overweight or obese is a serious health problem connected with some leading causes of death, including diabetes, stroke, and heart disease, and is associated with an increased risk of certain types of cancer

This creates a unique constraint that differs from general obesity treatment: Calories must be reduced, but not indiscriminately Appetite suppression can help adherence, but cannot eliminate hunger entirely Protein intake, meal timing, and recovery must remain intact As next-generation incretin-based therapies gain attention, two investigational compounds are frequently discussed in this context: survodutide and retatrutide

"It is just not worth losing your life to lose weight." If you have been affected by this report, help and support are available at BBC Action Line